BACKGROUND: Pelvic irradiation was once a common treatment for dysfunctiona
l uterine bleeding (DUB). Today the majority of women with DUB are successf
ully treated with hormonal therapy; patients unresponsive to hormonal thera
py may require endometrial ablation or hysterectomy. We present a patient w
ith severe, intractable DUB and contraindications to surgery who was treate
d wit intracavitary radiotherapy.
CASE: A 39-year-old, 150-cm-tall, 310-kg woman was referred for management
of severe DUB refractory to medical management. The bleeding was successful
ly treated wit intracavitary cesium. Hysterectomy was not recommended due t
o the operative risks posed by the patient's massive obesity. Because of te
chnical difficulties during a previous dilation and curettage and the expen
se of long-term GnRH agonist therapy, the patient elected to undergo intrac
avitary radiotherapy.
CONCLUSION: In selected patients, intracavitary radiotherapy can be used to
treat DUB when conventional therapy fails or is contraindicated.