Cutaneous malakoplakia: A report of two cases with the use of anti-BCG forthe detection for micro-organisms

Malakoplakia is an uncommon granulomatous infectious disease that is found primarily in the genitourinary tract, bur may rarely involve the skin. Hist ologic findings are marked by the presence of foamy macrophages containing basophilic concentric spherules, the Michaelis-Gutman bodies. Micro-organis ms are not readily identifiable. Immunostaining with polyclonal anti-mycoba cterium bovis (BCG) has been described as a method of identifying bacterial and fungal organisms in situations where organisms may be sparse. We repor t 2 cases of cutaneous malakoplakia with demonstration of organisms by immu nostaining with anti-BCG antibodies.