How well do patients with exstrophy actually void?

Purpose: Achieving continence and preserving renal function are goals in th e care of patients with bladder exstrophy. The Young-Dees-Leadbetter bladde r neck reconstruction should ideally provide continence and normal voiding dynamics without the need for intermittent catheterization. We review our e xperience with bladder neck reconstruction in this population with emphasis on voiding dynamics among those patients doing well. Materials and Methods: We retrospectively analyzed all patients with the ex strophy-epispadias complex seen at our institutions since 1985. We reviewed staged reconstruction in 53 patients, including 31 with classic bladder ex strophy, 4 with exstrophy variants and 18 with incontinent epispadias. Pati ents with additional neurogenic dysfunction were excluded from study. Subje ctive and objective data regarding voiding function and complications were collected. Results: Complete reconstruction for continence was performed in 38 cases, of which 11 that required bladder augmentation with bladder neck reconstruc tion or who had a different primary continence procedure were excluded from study. The remaining 27 patients treated With the Young-Dees-Leadbetter bl adder neck reconstruction had 2 or more years of followup (mean 5.9). Dry i ntervals of at least 2 hours were achieved by 18 patients and all were cons idered by parents to void well. Despite near or total subjective continence and "good" voiding, 13 of these 18 patients (72%) have clinical problems r elated to emptying, which include recurrent urinary tract infect ions in 10 , epididymitis in 2 and bladder calculi in 4. Objective urodynamic paramete rs confirm poor voiding in most patients. Conclusions: Bladder neck reconstruction in patients with exstrophy can ach ieve continence without intermittent catheterization. In our experience pat ients who achieve these goals have an alarming frequency of clinical and ur odynamic problems related to emptying. One must question the normalcy of th e voiding pattern and price to achieve continence among patients with exstr ophy.