Pax2, Otx2, Gbx2 and Fgf8 expression in early otic vesicle development

Authors
Hidalgo-Sanchez, M Alvarado-Mallart, RM Alvarez, IS
Citation
M. Hidalgo-sanchez et al., Pax2, Otx2, Gbx2 and Fgf8 expression in early otic vesicle development, MECH DEVEL, 95(1-2), 2000, pp. 225-229
Citations number
12
Categorie Soggetti
Cell & Developmental Biology
Journal title
MECHANISMS OF DEVELOPMENT
ISSN journal
09254773 → ACNP
Volume
95
Issue
1-2
Year of publication
2000
Pages
225 - 229
Database
ISI
SICI code
0925-4773(200007)95:1-2<225:POGAFE>2.0.ZU;2-6
Abstract
The inner ear is a suitable system to study the mechanisms involved in the specification of different functional domains during morphogenesis. Using s ingle and double in situ hybridization (ISH) we show that three transcripti on factors (Otx2, Gbx2 and Pax2) and a member of the fibroblast growth fact or family (Fgf8) could participate in the compartmentalization of the otic vesicle and in the formation of the acoustic-vestibular ganglion. (C) 2000 Elsevier Science ireland Ltd. All rights reserved.