Shigella, the causative agent of bacillar dysentery, invades colonic epithe
lial cells and moves intracellularly to spread from cell to cell. The proce
sses of Shigella entry, determined by the Ipa proteins, and of actin-based
motility, dependent on the IcsA/VirG protein, represent different levels of
bacterial manipulation of the cell cytoskeleton. (C) 2000 Editions scienti
fiques et medicales Elsevier SAS.