AIDS myelopathy is not associated with elevated HIV viral load in cerebrospinal fluid

Authors
Geraci, A Di Rocco, A Liu, M Werner, P Tagliati, M Godbold, J Simpson, D Morgello, S
Citation
A. Geraci et al., AIDS myelopathy is not associated with elevated HIV viral load in cerebrospinal fluid, NEUROLOGY, 55(3), 2000, pp. 440-442
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
55
Issue
3
Year of publication
2000
Pages
440 - 442
Database
ISI
SICI code
0028-3878(20000808)55:3<440:AMINAW>2.0.ZU;2-5
Abstract
The pathogenesis of AIDS-associated myelopathy is unknown. Elevated HIV-1 v iral load in CSF has been associated with cognitive impairment. The authors investigated if a similar association exists in patients with myelopathy, The authors evaluated levels of HIV-1 RNA in the CSF of 16 individuals with AIDS myelopathy and in 16 nonmyelopathic HIV-infected control subjects. Th ere was no correlation between levels of HIV-1 RNA and the presence or seve rity of myelopathy.