Angiogenesis in metastatic verrucous carcinoma of the uterine cervix

Authors
Matsumoto, Y Ishiko, O Nishimura, S Ogita, S Kubota, K Haba, T Wakasa, K
Citation
Y. Matsumoto et al., Angiogenesis in metastatic verrucous carcinoma of the uterine cervix, ONCOL REP, 7(5), 2000, pp. 1079-1082
Citations number
11
Categorie Soggetti
Oncology
Journal title
ONCOLOGY REPORTS
ISSN journal
1021335X → ACNP
Volume
7
Issue
5
Year of publication
2000
Pages
1079 - 1082
Database
ISI
SICI code
1021-335X(200009/10)7:5<1079:AIMVCO>2.0.ZU;2-Y
Abstract
A 65-year old woman operated on for verrucous carcinoma of the uterine cerv ix 13 years previously was found to have multiple small recurrent tumors in the retroperitoneal space. Tumor cell expression of vascular endothelial g rowth factor (VEGF) and platelet-derived endothelial cell growth factor (PD -ECGF) was investigated at the second operation. Expression of VEGF was str ongly positive in the tumor cells and expression of PD-ECGF was strongly po sitive in both the tumor cells and the interstitial cells.