Nonracemic 2-diazo-1-oxiranyl-ethanone, a versatile chiral epoxide educt in diazocarbonyl reactions

Authors
Groarke, M McKervey, MA Miel, H Nieuwenhuyzen, M
Citation
M. Groarke et al., Nonracemic 2-diazo-1-oxiranyl-ethanone, a versatile chiral epoxide educt in diazocarbonyl reactions, ORG LETT, 2(16), 2000, pp. 2393-2395
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
16
Year of publication
2000
Pages
2393 - 2395
Database
ISI
SICI code
1523-7060(20000810)2:16<2393:N2AVCE>2.0.ZU;2-V
Abstract
[GRAPHICS] (S)-(-)-2-Diazo-1-oxiranyl-ethanone, prepared in two steps from (R)-(+)-gly cidol, has been employed as an intermediate in several characteristic diazo carbonyl reactions to yield novel, nonracemic products including an epoxy q uinoxaline and epoxy thiazoles and oxazoles.