Jc. Bradley et al., A RAPID AND EFFICIENT PREPARATION OF LINEAR AND MACROCYCLIC POLYAMINEBOLAPHILES, Synthetic communications, 27(16), 1997, pp. 2833-2845
The preparation of linear polyamine bolaphiles via a highly efficient
and rapid synthetic strategy avoiding column chromatography is describ
ed. Cyclization of these compounds affords a ready access to macrocycl
ic polyamine bolaphiles. This approach represents a significant improv
ement over the original synthetic protocol.