Seven species of the genus Argyranthemum were studied for antimicrobia
l and cytotoxic activities. Argyranthemum adauctum, A. foeniculaceum a
nd A. frutescens showed antimicrobial activity against Grampositive an
d Gram-negative bacteria and cytotoxic activity against HeLa and Hep-2
cell lines. Two new acetylenic compounds, frutescinol isovalerate and
3'-demethyl frutescinol isovalerate, were isolated from A. frutescens
and their structures elucidated by spectroscopic studies. (C) 1997 El
sevier Science Ltd. All rights reserved.