Insect hosts can survive infection by parasitoids using the encapsulation p
henomenon. In Drosophila melanogaster the abilities to encapsulate the wasp
species Leptopilina boulardi and Asobara tabida each involve one major gen
e. Both resistance genes have been precisely localized on the second chromo
some, 35 centimorgans apart. This result clearly demonstrates the involveme
nt of at least two separate genetic systems in Drosophila resistance to par
asitoid wasps. The resistance genes to L. boulardi and A. tabida are not cl
ustered as opposed to many plant resistance genes to pathogens cloned to da
te.