Diagnostic tests for hepatitis C virus have improved dramatically over the
past decade. Highly accurate tests are now available for screening patients
for possible hepatitis C infections nod confirming the presence of active
viral infection. HCV RNA levels and genotype are very useful in assessing t
he likelihood of response to antiviral therapy and in guiding the optimum d
uration of treatment. Absence of detectable HCV RNA using PCR methodology h
as become the gold standard of successful treatment of patients with chroni
c hepatitis C. The various tests for hepatitis C are expensive and have the
ir limitations. However, selective use of these assays has greatly improved
the care of patients with chronic hepatitis C.