Diagnostic testing for hepatitis C

Citation
Rl. Carithers et al., Diagnostic testing for hepatitis C, SEM LIV DIS, 20(2), 2000, pp. 159-171
Citations number
96
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
SEMINARS IN LIVER DISEASE
ISSN journal
02728087 → ACNP
Volume
20
Issue
2
Year of publication
2000
Pages
159 - 171
Database
ISI
SICI code
0272-8087(2000)20:2<159:DTFHC>2.0.ZU;2-6
Abstract
Diagnostic tests for hepatitis C virus have improved dramatically over the past decade. Highly accurate tests are now available for screening patients for possible hepatitis C infections nod confirming the presence of active viral infection. HCV RNA levels and genotype are very useful in assessing t he likelihood of response to antiviral therapy and in guiding the optimum d uration of treatment. Absence of detectable HCV RNA using PCR methodology h as become the gold standard of successful treatment of patients with chroni c hepatitis C. The various tests for hepatitis C are expensive and have the ir limitations. However, selective use of these assays has greatly improved the care of patients with chronic hepatitis C.