The preparation of 4,5-dihydro-3-aryl-naphth-[1,2-c]-isoxazoles from dilithiated 1-tetralone oxime and aromatic esters

Authors
Beam, CF Schady, DA Rose, KL Kelley, W Rakkhit, R Hornsby, CD Studer-Martinez, SL
Citation
Cf. Beam et al., The preparation of 4,5-dihydro-3-aryl-naphth-[1,2-c]-isoxazoles from dilithiated 1-tetralone oxime and aromatic esters, SYN COMMUN, 30(18), 2000, pp. 3391-3404
Citations number
38
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
30
Issue
18
Year of publication
2000
Pages
3391 - 3404
Database
ISI
SICI code
0039-7911(2000)30:18<3391:TPO4FD>2.0.ZU;2-P
Abstract
Dilithiated 1-tetralone oxime was prepared in excess lithium diisopropylami de and condensed with a variety of esters followed by acid cyclization of C -acylated intermediates to substituted 4,5-dihydronaphth-[1,2-c]isoxazoles.