RA-dimer A, a novel dimeric antitumor bicyclic hexapeptide from Rubia cordifolia L.

Authors
Hitotsuyanagi, Y Aihara, T Takeya, K
Citation
Y. Hitotsuyanagi et al., RA-dimer A, a novel dimeric antitumor bicyclic hexapeptide from Rubia cordifolia L., TETRAHEDR L, 41(32), 2000, pp. 6127-6130
Citations number
8
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
32
Year of publication
2000
Pages
6127 - 6130
Database
ISI
SICI code
0040-4039(20000805)41:32<6127:RAANDA>2.0.ZU;2-E
Abstract
A novel antitumor bicyclic hexapeptide dimer, RA-dimer A (3), was isolated from the roots of Rubia cordifolia L. The structure of 3 was determined by analysis of spectroscopic data and chemical correlations. Peptide 3 is the first example of the RA congeners having a dimeric structure. (C) 2000 Else vier Science Ltd. All rights reserved.