A generalization of the Hulthen potential is presented on the basis of an a
pproach that uses the factorization of a general Hamiltonian by means of a
specific model of operational equations with the structure similar to beta(
p)(r) -/+ (d/dr). To achieve this goal, the treatment of the V-Hs(r) standa
rd Hulthen potential for bound s states is carried out by proposing a parti
cular beta(p)(r) ansatz to identify V-Hs(r) by means of a particular Riccat
i-type relationship. Once the identification has been achieved, the general
ized Hulthen potential is obtained straightforwardly with the aid of a gene
ral Riccati formula. As expected, the Hamiltonian of the generalized Hulthe
n potential is isospectral when compared with the corresponding standard Ha
miltonian. Moreover, according to the Darboux transform there exists a modi
fied Hulthen potential which is also isospectral. We show that the latter i
s just a particular case of the generalized Hulthen interaction model.