The Institute of Medicine recommends that short women gain less weight duri
ng pregnancy than taller women in order to reduce the risk of high birthwei
ght, which can lead to feto-pelvic disproportion. This recommendation, howe
ver, is based on clinical judgment rather than on epidemiologic evidence, a
s few studies have examined the relationships between maternal height, preg
nancy weight gain, and infant birthweight. Our objective was to determine w
hether maternal height is an independent risk factor for infant birthweight
and to assess whether maternal height modifies the effect of pregnancy wei
ght gain on infant birthweight. We examined the relationship between matern
al height and infant birthweight in a multiethnic cohort of 8,870 women wit
h uncomplicated pregnancies who delivered singleton infants at the Universi
ty of California, San Francisco, 1980-1990. Using multiple linear regressio
n, we modeled the contribution of height and weight gain to birthweight in
four different ethnic groups. Increasing maternal height was significantly
and positively associated with infant birthweight in White, Black, and Asia
n women, but not Hispanic women. The relationship between pregnancy weight
gain and infant birthweight was not modified by maternal height. (C) 2000 W
iley-Liss, Inc.