Disseminated intravascular coagulation and purpura fulminans secondary to infection

Authors
Faust, SN Heyderman, RS Levin, M
Citation
Sn. Faust et al., Disseminated intravascular coagulation and purpura fulminans secondary to infection, BEST P R C, 13(2), 2000, pp. 179-197
Citations number
144
Categorie Soggetti
Hematology
Journal title
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
ISSN journal
15216926 → ACNP
Volume
13
Issue
2
Year of publication
2000
Pages
179 - 197
Database
ISI
SICI code
1521-6926(200006)13:2<179:DICAPF>2.0.ZU;2-Q
Abstract
Infection is one of the commonest causes of disseminated intravascular coag ulation (DIC). DIC is a complex disorder that results from an imbalance of the pro- and anticoagulant regulatory pathways. This chapter will explain t he cellular and molecular basis of the disorder and consider the rationale behind current and experimental treatment strategies.