Design and synthesis of AB(3)-type (A = 1,3,5-benzenetricarbonyl unit; B =Glu diOMe or Glu(7) octa OMe) peptide dendrimers: Crystal structure of thefirst generation

Authors
Ranganathan, D Kurur, S Gilardi, R Karle, IL
Citation
D. Ranganathan et al., Design and synthesis of AB(3)-type (A = 1,3,5-benzenetricarbonyl unit; B =Glu diOMe or Glu(7) octa OMe) peptide dendrimers: Crystal structure of thefirst generation, BIOPOLYMERS, 54(4), 2000, pp. 289-295
Citations number
40
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOPOLYMERS
ISSN journal
00063525 → ACNP
Volume
54
Issue
4
Year of publication
2000
Pages
289 - 295
Database
ISI
SICI code
0006-3525(200010)54:4<289:DASOA(>2.0.ZU;2-X
Abstract
The first generation molecule of glutamic acid-based dendrons on a 1,3,5-be nzenetricarbonyl core leads to a cylindrical assembly as demonstrated by si ngle crystal x-ray diffraction. The benzene pi-pi stack (A) is stabilized b y vertical NH ... O=C hydrogen bonding with each subunit participating in t hree intermolecular hydrogen bonds related by three-fold rotation symmetry. (C) 2000 John Wiley & Sons, Inc.dagger