The rat vertex-Middle Latency Auditory-Evoked Potential as indicator of anaesthetic depth: a comparison with evoked-reflex testing

Authors
Haberham, ZL van den Brom, WE Venker-van Haagen, AJ de Groot, HNM Baumans, V Hellebrekers, LJ
Citation
Zl. Haberham et al., The rat vertex-Middle Latency Auditory-Evoked Potential as indicator of anaesthetic depth: a comparison with evoked-reflex testing, BRAIN RES, 873(2), 2000, pp. 287-290
Citations number
15
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH
ISSN journal
00068993 → ACNP
Volume
873
Issue
2
Year of publication
2000
Pages
287 - 290
Database
ISI
SICI code
0006-8993(20000811)873:2<287:TRVLAP>2.0.ZU;2-4
Abstract
We investigated whether components from the rat Vx-MLAEP could be used to a ssess depth of anaesthesia induced by propofol. Propofol decreased MLAEP am plitudes and increased latencies. We propose that the P-16-N-22 wave in the rat MLAEP is similar to the human P1, and that recovery of this wave durin g propofol anaesthesia correlates with behavioural measures of the regainin g of consciousness. (C) 2000 Elsevier Science B.V. All rights reserved.