Context: Measurement of pulsus paradoxus (PP) is one of several measures pr
eviously advocated in the National Heart, Lung, and Blood Institute asthma
management guidelines: a pulsus of > 12 mm Hg warranted hospital admission.
It is one of only a few measures that is not effort dependent and therefor
e important in the evaluation of patients with asthma.
Objective: Determination of physician accuracy in measuring PP.
Design: A model of induced PP in a trained healthy subject without respirat
ory disease was constructed with a fixed inspiratory resistance with measur
ement of inspiratory air pressure and beat-to-beat BP noninvasively,
Setting: Laboratory.
Participants: Attending physicians from emergency medicine and critical car
e disciplines who served as consecutive examiners of the trained reference
subject generating known PP.
Interventions: A total of 19 attending physicians were assessed for ability
in measuring PP by sphygmomanometry and by palpation. The reference subjec
t generated 4 degrees of PP sequentially, with each examiner blinded to the
value of negative inspiratory pressure and PP, Examiners first assessed PP
qualitatively by palpation, followed by its measurement within 2 min.
Main outcome measure: Proximity of physician-measured PP (PPm) to true PP (
PPt). Results: At inspiratory pressures of -10, -15, -20, and -25 mm Hg, PP
t was 13.7, 16.2, 19.1, and 20.7 mm Hg, respectively (F = 14.8, p < 0.0001;
analysis of variance [ANOVA]). At the same pressures, PPm was 13.1, 17.5,
17.7, and 18.0 mm Hg (p > 0.10; ANOVA). Linear regression of PPm against PP
t for each examiner revealed a slope (SE) of 0.53 (0.23), and not a 1:1 rel
ationship.
Conclusions: Past and present guidelines do not account for the challenges
in measuring PP, especially in tachypneic patients. Sphygmomanometric deter
mination of PP should be augmented by new aids developed through technologi
cal innovation.