New approaches in the treatment of bacterial infections

Citation
K. Bush et M. Macielag, New approaches in the treatment of bacterial infections, CURR OP C B, 4(4), 2000, pp. 433-439
Citations number
60
Categorie Soggetti
Biochemistry & Biophysics
Journal title
CURRENT OPINION IN CHEMICAL BIOLOGY
ISSN journal
13675931 → ACNP
Volume
4
Issue
4
Year of publication
2000
Pages
433 - 439
Database
ISI
SICI code
1367-5931(200008)4:4<433:NAITTO>2.0.ZU;2-Y
Abstract
Recently, several new drugs for the treatment of bacterial infections have been developed. Quinupristin/dalfopristin, moxifloxacin and gatifloxacin ha ve been approved throughout the world for clinical use. Levofloxacin has be en approved for the treatment of community-acquired pneumonia caused by pen icillin-resistant Streptococcus pnuemoniae. The Food and Drug Administratio n has approved linezolid for clinical use, and new drug applications for ge mifloxacin and telithromycin were filed. Other new targets have surfaced in the quest for novel antibacterial agents.