Infection-resistant nonleachable materials for urologic devices

Bacterial colonization is the primary clinical problem faced by the surgeon and medical device innovator. Despite the absence of effective systemic tr eatment, medical implants and devices have been deployed with increasing su ccess over the past five decades. Infection-resistant materials (IRMs) are a relatively recent addition to the science of implant and device developme nt. The first IRM utilized leachable antimicrobial agents. Nonleachable tec hnologies are being developed, some of which have the potential to make org an replacement even more successful in the future.