A radical based addition-elimination route for the preparation of indoles

Citation
Ja. Murphy et al., A radical based addition-elimination route for the preparation of indoles, J CHEM S P1, (15), 2000, pp. 2395-2408
Citations number
89
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14704358 → ACNP
Issue
15
Year of publication
2000
Pages
2395 - 2408
Database
ISI
SICI code
1470-4358(2000):15<2395:ARBARF>2.0.ZU;2-1
Abstract
Indoles, including tricyclic derivatives, are produced by cyclisations of a ryl radicals onto vinyl halides followed by elimination of halide radical a nd tautomerism of the resulting product; the aryl radicals are produced usi ng "clean methodology" either by reaction of iodide ions with arenediazoniu m salts or by reaction of phosphorus-centred radicals with aryl iodides.