NO SHORT-TERM EFFECTS OF HIGH-FREQUENCY ELECTROMAGNETIC-FIELDS ON THEMAMMALIAN PINEAL-GLAND

There is ample experimental evidence that changes of earth-strength st atic magnetic fields, pulsed magnetic fields, or alternating electric fields (60 Hz) depress the nocturnally enhanced melatonin synthesis of the pineal gland of certain mammals. No data on the effects of high-f requency electromagnetic fields on melatonin synthesis is available. I n the present study, exposure to 900 MHz electromagnetic fields [0.1 t o 0.6 mW/cm(2), approximately 0.06 to 0.36 W/kg specific absorption ra te (SAR) in rats and 0.04 W/kg in Djungarian hamsters; both continuous and/or pulsed at 217 Hz, for 15 min to 6 h] at day or night had no no table short-term effect on pineal melatonin synthesis in male and fema le Sprague-Dawley rats and Djungarian hamsters. Pineal synaptic ribbon profile numbers (studied in rats only) were likewise not affected. Th e 900 MHz electromagnetic fields, unpulsed or pulsed at 217 Hz, as app lied in the present study, have no short-term effect on the mammalian pineal gland. (C) 1997 Wiley-Liss, Inc.