Citation
D. Benedek et al., Atypical chronic myeloid leukaemia with trisomy 21 mosaicism as a sole chromosomal abnormality, LEUK LYMPH, 38(5-6), 2000, pp. 639
Citations number
15
Categorie Soggetti
Hematology,"Onconogenesis & Cancer Research
Journal title
LEUKEMIA & LYMPHOMA
ISSN journal
10428194
→ ACNP
Volume
38
Issue
5-6
Year of publication
2000
Database
ISI
SICI code
1042-8194(200008)38:5-6<639:ACMLWT>2.0.ZU;2-6
Abstract
We present a 46-year-old patient with Ph-chromosome negative, bcr-negative
chronic myeloid leukaemia (CML) in accelerated phase with a clonal trisomy
21 in the leukaemic blast cells. A rapid progress of disease with appearanc
e of monocytosis is described, showing similar features to chronic myelomon
ocytic leukaemia (CMML), Heterogeneous characteristics and possible distinc
tion of these two entities are discussed.