Complement component 9 deficiency is not a susceptibility factor for SLE

Authors
Kanemitsu, S Ihara, K Kira, R Kaku, Y Sakai, K Tsuzaka, K Takeuchi, T Hara, T
Citation
S. Kanemitsu et al., Complement component 9 deficiency is not a susceptibility factor for SLE, LUPUS, 9(6), 2000, pp. 456-457
Citations number
10
Categorie Soggetti
Rheumatology
Journal title
LUPUS
ISSN journal
09612033 → ACNP
Volume
9
Issue
6
Year of publication
2000
Pages
456 - 457
Database
ISI
SICI code
0961-2033(2000)9:6<456:CC9DIN>2.0.ZU;2-I
Abstract
Almost all complement component 9 (C9) deficiency in Japan shows Arg95Stop mutation of C9 gene. Therefore, we studied the prevalence of Arg95Stop muta tion of C9 gene among 78 patients with SLE to elucidate the assocation of S LE and C9 deficiency. The Arg95Stop carrier frequency showed no significant difference between SLE patients and controls. Thus, C9 deficiency is not i mplicated in SLE susceptibility.