Quantification of cerebral blood flow by bolus tracking and artery spin tagging methods

This study deals with perfusion quantification in healthy volunteers using two types of dynamic magnetic resonance imaging (MRI) methods. Absolute cer ebral blood flow (CBF) measurements were performed in 11 subjects by applyi ng both bolus tracking of exogenous contrast agent and non-invasive arteria l spin labeling MRI techniques. Both methods produced CBF images with good tissue contrast and CBF values are in good agreement with literature data. The correlation between cerebral blood volume (CBV) and CBF is also discuss ed. (C) 2000 Elsevier Science inc. All rights reserved.