Depleted uranium is now widely used in the armor of military vehicles as we
ll as in kinetic-energy penetrators designed to defeat enemy armor, As a re
sult, the potential that personnel mill be wounded by depleted uranium frag
ments has increased. Because toxicities associated with depleted uranium fr
agments may ultimately require different treatment protocols than those use
d for traditional metal fragment injuries, a method to rapidly detect the p
resence of depleted uranium in surgically excised shrapnel fragments is req
uired. By treating the shrapnel fragment with an extracting agent, such as
nitric acid, for 5 minutes in an ultrasonic cleaner, sufficient metal is so
lubilized to allow for colorimetric detection using a pyridylazo dye. Altho
ugh several metals are capable of being detected under these conditions, th
e reaction can be made specific for depleted uranium through the use of mas
king agents such as sodium citrate and ethylenediaminetetraacetic acid. Thi
s procedure allows for the rapid (<15 minutes) extraction and detection of
depleted uranium in metal shrapnel fragments.