We report a 17-year-old hemodialysis patient with a rapidly growing maxilla
ry mass diagnosed as a brown tumor. Although successful control of the para
thyroid hormone (PTH) levels was achieved by treatment with vitamin D pulse
therapy, the lesion progressed, invaded the maxillary sinus, and caused se
vere eating and speech disabilities. No recurrence was observed following s
urgical excision. The differential diagnosis and considerations regarding t
he causes of the disease in a child, therapy options, and review of the lit
erature are presented.