FACILE AND GENERAL SYNTHESES OF 1-ALKYLTOXOFLAVIN AND 8-ALKYLFERVENULIN DERIVATIVES OF BIOLOGICAL SIGNIFICANCE BY THE REGIOSPECIFIC ALKYLATION OF REUMYCIN (1-DEMETHYLTOXOFLAVIN, 8-DEMETHYL-FERVENULIN) DERIVATIVES

Authors
NAGAMATSU T YAMASAKI H
Citation
T. Nagamatsu et H. Yamasaki, FACILE AND GENERAL SYNTHESES OF 1-ALKYLTOXOFLAVIN AND 8-ALKYLFERVENULIN DERIVATIVES OF BIOLOGICAL SIGNIFICANCE BY THE REGIOSPECIFIC ALKYLATION OF REUMYCIN (1-DEMETHYLTOXOFLAVIN, 8-DEMETHYL-FERVENULIN) DERIVATIVES, Heterocycles, 45(4), 1997, pp. 643-650
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
45
Issue
4
Year of publication
1997
Pages
643 - 650
Database
ISI
SICI code
0385-5414(1997)45:4<643:FAGSO1>2.0.ZU;2-V
Abstract
Regiospecific alkylation of reumycins (6) under alkaline conditions wi th a dialkyl sulfate or alkyl halide in dioxane and in DMF to provide 1-alkyltoxoflavins (5) of biological significance and 8-alkylfervenuli ns (7), respectively, is described.