A fully relativistic model for the description of exclusive (e,e'p) reactio
ns off nuclear targets at high energies and momentum transfers is outlined.
It is based on the eikonal approximation for the ejectile scattering wave
function and a relativistic mean-field approximation to the Walecka model.
Results for C-12(e,e'p) and O-16(e,e'p) differential cross sections and sep
arated structure functions are presented for four-momenta in the range 0.8
less than or equal to Q(2) less than or equal to 20 (GeV/c)(2). The regions
of applicability of the eikonal approximation are studied and observed to
be confined to proton knockout in a relatively small cone about the momentu
m transfer. A simple criterion defining the boundaries of this cone is dete
rmined. The Q(2) evolution of the effect of off-shell ambiguities on the di
fferent (e,e'p) structure functions is addressed. At sufficiently high valu
es of Q(2) their impact on the cross sections is illustrated to become prac
tically negligible. It is pointed out that for the whole range of Q(2) valu
es studied here, the bulk of the relativistic effects arising from the coup
ling between the lower components in the wave functions, is manifesting its
elf in the longitudinal-transverse interference term.