Regio- and enantioselective carbolithiation of non-activated C=C bonds

Authors
Norsikian, S Baudry, M Normant, JF
Citation
S. Norsikian et al., Regio- and enantioselective carbolithiation of non-activated C=C bonds, TETRAHEDR L, 41(34), 2000, pp. 6575-6578
Citations number
24
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
34
Year of publication
2000
Pages
6575 - 6578
Database
ISI
SICI code
0040-4039(20000819)41:34<6575:RAECON>2.0.ZU;2-V
Abstract
Primary alkyllithiums in the presence of (-)-sparteine, add to terminal con jugated dienes. They also add to 2,4-pentadien-1-ols if they are substitute d on C(5), and give rise to allyllithium intermediates, 2-Alkylalkan-1-ols have thus been prepared with ee's up to 74%. (C) 2000 Elsevier Science Ltd, All rights reserved.