Reverse Brook rearrangement of 2-alkynyl trialkylsilyl ether. Synthesis ofoptically active (1-hydroxy-2-alkynyl)trialkylsilane

Authors
Sakaguchi, K Fujita, M Suzuki, H Higashino, M Ohfune, Y
Citation
K. Sakaguchi et al., Reverse Brook rearrangement of 2-alkynyl trialkylsilyl ether. Synthesis ofoptically active (1-hydroxy-2-alkynyl)trialkylsilane, TETRAHEDR L, 41(34), 2000, pp. 6589-6592
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
34
Year of publication
2000
Pages
6589 - 6592
Database
ISI
SICI code
0040-4039(20000819)41:34<6589:RBRO2T>2.0.ZU;2-D
Abstract
A new method for the synthesis of optically active alpha-hydroxyalkynylsila ne 3 is described. The key step of the conversion to 3 was the use of the r everse Brook rearrangement of the 2-alkynyl silyl ether 2. (C) 2000 Elsevie r Science Ltd. All rights reserved.