A short and efficient synthesis of N-Cbz-galantinic acid under promoter control on enantioselective acyclic stereoselection based on chiral oxazaborolidinone-promoted aldol reactions

Authors
Kiyooka, S Goh, K Nakamura, Y Takesue, H Hena, MA
Citation
S. Kiyooka et al., A short and efficient synthesis of N-Cbz-galantinic acid under promoter control on enantioselective acyclic stereoselection based on chiral oxazaborolidinone-promoted aldol reactions, TETRAHEDR L, 41(34), 2000, pp. 6599-6603
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
34
Year of publication
2000
Pages
6599 - 6603
Database
ISI
SICI code
0040-4039(20000819)41:34<6599:ASAESO>2.0.ZU;2-C
Abstract
An effective 'promoter control' on enantioselective acyclic stereoselection based on chiral oxazaboro-lidinone-promoted asymmetric aldol reactions has been found in the case of chiral N-protected alpha-amino aldehydes. An ena ntioselective synthesis of the title compound has been efficiently accompli shed by using a sequence of the aldol reaction. (C) 2000 Elsevier Science L td. All rights reserved.