L. Andersen et al., Treatment of breast-cancer-related lymphedema with or without manual lymphatic drainage - A randomized study, ACTA ONCOL, 39(3), 2000, pp. 399-405
A prospective randomized study was carried out to investigate whether the a
ddition of manual lymphatic drainage (MLD) to the standard therapy could im
prove treatment outcome in women with lymphedema of the ipsilateral arm aft
er breast cancer treatment. Forty-two patients were randomly assigned to re
ceive standard therapy or standard therapy plus MLD 8 times in 2 weeks and
training in self-massage. The standard therapy consisted of use of a compre
ssion garment, exercises and information about lymphedema and skin care. Th
e efficacy of treatment was evaluated by reduction in lymphedema volume dur
ing treatment and by improvement in symptoms potentially related to lymphed
ema. The patients were followed-up for a total of 12 months. The study show
ed that both groups obtained a significant reduction in edema and that MLD
did not contribute significantly to reduce edema volume.