A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy - A case report

Gemfibrozil-statin combination therapy is a well-known risk factor for myop athy and rhabdomyolysis, Cerivastatin is a currently available statin with dual elimination; it is therefore expected to cause less drug-drug interact ion. This case is the second reported case with severe rhabdomyolysis cause d by cerivastatin-gemfibrozil combination. Moreover, in this case, the rhab domyolysis was more severe and caused severe renal failure and death. The a uthors discuss how these drugs cause rhabdomyolysis and how rhabdomyolysis can cause renal failure.