Brachial plexopathy associated with diffuse edematous scleroderma

Peripheral nervous system (PNS) involvement is rare in systemic sclerosis ( SSc), usually restricted to peripheral nerve entrapment. To our knowledge, only one case of scleroderma with brachial plexus involvement has been repo rted previously. We report here on a 61-year-old woman with past history of limited cutaneous SSc who developed motor deficiency in the Left arm conco mittent with diffuse edematous scleroderma without evidence for trauma or c ompression of the brachial plexus. After six months intravenous pulse cyclo phosphamide therapy, dramatic improvement of skin and neurological involvem ent was observed.