We report a malignant uterine paraganglioma in a 41-year-old woman who unde
rwent a hysterectomy for meno-metrorrhagia. It was initially thought to be
a leiomyoma in necrobiosis, The clinical outcome was characterized by an ea
rly regional recurrence tin the left Fallopian tube). Later, vertebral and
lung metastasis occured, leading to death 22 months after the initial diagn
osis.
Paragangliomas are uncommon neuroendocrine tumors, related to pheochromocyt
omas. They are mainly found in the para-aortic and retroperitoneal region,
and less commonly in the pelvic area. Location in the uterus is extremely r
are: 5 cases were previously reported and only one malignant.