Comparative in vitro activities of ertapenem (MK-0826) against 1,001 anaerobes isolated from human intra-abdominal infections

Authors
Goldstein, EJC Citron, DM Merriam, CV Warren, Y Tyrrell, KL
Citation
Ejc. Goldstein et al., Comparative in vitro activities of ertapenem (MK-0826) against 1,001 anaerobes isolated from human intra-abdominal infections, ANTIM AG CH, 44(9), 2000, pp. 2389-2394
Citations number
15
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
9
Year of publication
2000
Pages
2389 - 2394
Database
ISI
SICI code
0066-4804(200009)44:9<2389:CIVAOE>2.0.ZU;2-2
Abstract
By using an agar dilution method, the comparative in vitro activities of er tapenem (MK-0826) were studied against 1,001 anaerobes isolated from human intra-abdominal infections in 17 countries worldwide. MK-0826 was uniformly active against all isolates, including all Bacteroides fragilis group spec ies isolates, with the exception of 12 of 61 (20%) strains of Bilophila wad sworthia, 3 strains of lactobacilli, and 1 isolate of Acidaminococcus ferme ntans. Geographical variation in activity was not observed.