This paper presents performance indicators for the Brazilian cancer, cardio
vascular and malaria research areas from 1981 to 1995. The data show an inc
reasing number of papers since 1981 and author numbers indicate a continuou
s growth of the scientific community and suggest an expected impact of scie
ntific activity on biomedical education. The data also characterize cardiov
ascular research as a well-established area and cancer research as a faster
growing consolidating field. The 1989-1994 share of Brazilian articles amo
ng world publications shows a growing trend for the cancer (1.61) and cardi
ovascular (1.59) areas, and a decrease for the malaria area (0.89). The bur
den of the three diseases on society is contrasted by the small number of c
onsolidated Brazilian research groups, and a questionable balance of themat
ic activity, especially with regard to malaria. Brazilian periodicals play
an important role in increasing the international visibility of science pro
duced in the country. Cancer and cardiovascular research is strongly concen
trated in the Southeastern and in Southern regions of Brazil, especially in
Sao Paulo (at least one address from Sao Paulo in 64.5% of the 962 cancer
articles and in 66.9% of the 2250 cardiovascular articles, the second state
being Rio de Janeiro with at least one address in 14.1 and 11% of those ar
ticles, respectively). Malaria research (468 articles) is more evenly distr
ibuted across the country, following the pattern of the endemic distributio
n of the disease. Surveying these national indicator trends can be useful t
o establish policies in the decision process about health sciences, medical
education and public health.