Characterisation of a sugar epimerase enzyme involved in the biosynthesis of a vancomycin-group antibiotic

Authors
Kirkpatrick, PN Scaife, W Hallis, TM Liu, H Spencer, JB Williams, DH
Citation
Pn. Kirkpatrick et al., Characterisation of a sugar epimerase enzyme involved in the biosynthesis of a vancomycin-group antibiotic, CHEM COMMUN, (17), 2000, pp. 1565-1566
Citations number
14
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
17
Year of publication
2000
Pages
1565 - 1566
Database
ISI
SICI code
1359-7345(2000):17<1565:COASEE>2.0.ZU;2-O
Abstract
An enzyme involved in the biosynthesis of the 4-epi-vancosamine substituent s of a vancomycin group antibiotic has been expressed and its role as a TDP -4-keto-6-deoxyglucose-3,5-epimerase demonstrated.