Highly efficient enantioselective synthesis of optically active dihydropyrones by chiral titanium(iv) (5,5 ',6,6 ',7,7 ',8,8 '-octahydro-1,1 '-bi-2-naphthol) complexes

Authors
Wang, B Feng, XM Cui, X Liu, H Jiang, YZ
Citation
B. Wang et al., Highly efficient enantioselective synthesis of optically active dihydropyrones by chiral titanium(iv) (5,5 ',6,6 ',7,7 ',8,8 '-octahydro-1,1 '-bi-2-naphthol) complexes, CHEM COMMUN, (17), 2000, pp. 1605-1606
Citations number
18
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
17
Year of publication
2000
Pages
1605 - 1606
Database
ISI
SICI code
1359-7345(2000):17<1605:HEESOO>2.0.ZU;2-M
Abstract
The asymmetric hetero-Diels-Alder reaction of Danishefsky's diene and an al dehyde catalyzed by 20 mol% chiral H-8-BINOL-Ti(iv) affords the correspondi ng 2-substitutent-2,3-dihydro-4H-pyran-4-one with ees of up to 99% under mi ld reaction conditions.