Determination of carbetamide in groundwater by micro liquid-liquid extraction and gas chromatography-mass spectrometry

A method is proposed for the determination of carbetamide in water below Eu ropean Union guidelines (detection limit, DI below 0.1 mu g L-1). Micro liq uid-liquid extraction with dichloromethane affords carbetamide which is con verted to aniline by hydrolysis. identification and quantification of anili ne was performed by GC-MS. The retention time was 4.24 min. Quantification was achieved by single-ion monitoring (SIM) at m / z 66 and 93. Clean-up is not necessary before SIM. Deuterated anthracene (H-2(10)-anthracene) was u sed as internal standard. The method was used to determine carbetamide in d ifferent types of water sample spiked at very low concentration levels (0.1 3 - 10.00 mu g L-1). The DI was 0.04 mu g L-1. The effect of the presence o f other carbamates was also studied.