Polymerizable derivatives of (+)-1(S)-p-nitrophenyl-2(S)amino-propane-l, 3-diol

Template molecules have been used to generate cavities in polymer materials . If chiral template molecules are used, then it is to be expected that the prepared cavities will also be chiral. An attempt has been made to convert (+)-1(S)-p-nitrophenyl-2(S)-amino-propane-1,3-diol, a by-product in the sy nthesis of chloroamphenicol, into polymerizable derivatives and to incorpor ate these derivatives into polymers. Preferred conformations of the monomer s were calculated by means of the cosmos force field. The results are compa red with those of the spectroscopic characterization of the substances.