Successful treatment of bilateral renal fungal balls with liposomal amphotericin B and fluconazole in an extremely low birth weight infant

At the age of 8 weeks, an extremely low birth weight infant (gestational ag e 26 0/7 weeks, birth weight 740 g) had nan-obstructing bilateral renal fun gal balls. Urine cultures had repeatedly grown Candida albicans. Combinatio n therapy with liposomal amphotericin B intravenously and fluconazole orall y was administered for 6 weeks. Monotherapy with fluconazole was then conti nued until complete resolution of the renal fungal balls. Conclusion Combination therapy with liposomal amphotericin B and fluconazol e was successful in eliminating non-obstructing bilateral renal fungal ball s and obviated the need for surgical intervention.