N-Substituted 3-(arylamino)-4,5-dihydro-2H-benz[g]indazol-2-yl acetamides with anti-inflammatory and analgesic activities

Authors
Schenone, S Bruno, O Ranise, A Bondavalli, F Falcone, G Filippelli, W Rivaldi, B
Citation
S. Schenone et al., N-Substituted 3-(arylamino)-4,5-dihydro-2H-benz[g]indazol-2-yl acetamides with anti-inflammatory and analgesic activities, FARMACO, 55(5), 2000, pp. 383-388
Citations number
6
Categorie Soggetti
Pharmacology & Toxicology
Journal title
FARMACO
ISSN journal
0014827X → ACNP
Volume
55
Issue
5
Year of publication
2000
Pages
383 - 388
Database
ISI
SICI code
0014-827X(200005)55:5<383:N3AW>2.0.ZU;2-L
Abstract
A series of substituted 3-(arylamino)-4,5-dihydro-2H-benz[g]indazol-2-yl ac etamides was synthesized and tested in comparison with former analogues. Th e title compounds showed only weak antiarrhythmic properties but good anti- inflammatory and antinociceptive activity, particularly evident in the morp holino derivative. (C) 2000 Published by Elsevier Science S.A. All rights r eserved.