Synthesis and evaluation of antimitotic activity of alkylated 2-amino-1,3,4-oxadiazole derivatives

Authors
Rai, KML Linganna, N
Citation
Kml. Rai et N. Linganna, Synthesis and evaluation of antimitotic activity of alkylated 2-amino-1,3,4-oxadiazole derivatives, FARMACO, 55(5), 2000, pp. 389-392
Citations number
8
Categorie Soggetti
Pharmacology & Toxicology
Journal title
FARMACO
ISSN journal
0014827X → ACNP
Volume
55
Issue
5
Year of publication
2000
Pages
389 - 392
Database
ISI
SICI code
0014-827X(200005)55:5<389:SAEOAA>2.0.ZU;2-6
Abstract
Series of N-alkylated-2-amino-1,3,4-oxadiazoles (2) were synthesized via al kylation of 2-amino-1,3,4-oxadiazoles (1) under phase transfer condition. T his paper also describes the study of antimitotic activity of these molecul es by onion root tip method. (C) 2000 Elsevier Science S.A. All rights rese rved.