Background. It has been demonstrated that radio-guided surgery offers sever
al advantages in treating primary hyperparathyroidism. Even if it is consid
ered less helpful in renal hyperparathyroidism, it could be of tremendous a
dvantage in the treatment of persistent or recurrent secondary hyperparathy
roidism.
Methods. We report a case of recurrent secondary hyperparathyroidism treate
d by the use of radio-guided surgery. The preoperative assessment consistin
g of ultrasonography, magnetic resonance imaging, and 99mTc-sestamibi scint
igraphy identified a parathyroid in the upper mediastinum. The patient unde
rwent a radio-guided neck re-exploration that allowed a rapid localization
and excision of the ectopic gland, which was located in the anterosuperior
mediastinum, in front of the trachea, between the innominant and the left c
ommon carotid artery.
Results. The operative time was 45 minutes. The patient was discharged on t
he first postoperative day. A decrease in serum calcium End parathyroid hor
mone was observed subsequently. A follow-up of 6 months did not show any re
currence.
Conclusions. The case reported indicates that radio-guided surgery can help
surgeons detect parathyroid tissue in selected cases of renal hyperparathy
roidism. (C) 2000 John Wiley & Sons, Inc.