Connection between chromatographic data and biological data

There are no previous references to the direct use of GLC data in the corre lation of biological processes, but we show that GLC retention data can be used in the correlation of several such processes involving gaseous solutes . There are a number of reports of RP-HPLC and MEKC data being used in the correlation of biological processes, but they are mostly restricted as to t he number and type of solute studied. We show that if chromatographic data are used to obtain solvation descriptors for solutes, and if these descript ors are then used in the correlation of biological processes, that this ind irect connection is a much more powerful and generally applicable method th an is the direct connection between chromatographic data and biological dat a. (C) 2000 Elsevier Science B.V. All rights reserved.