F-theory on K3 admits non-BPS states that are represented as string junctio
ns extending between 7-branes. We classify the non-BPS states which are gua
ranteed to be stable on account of charge conservation and the existence of
a region of moduli space where the 7-branes supporting the junction can be
isolated from the rest of the branes. We find three possibilities; the 7-b
rane configurations carrying: (i) the D-1 algebra representing a D7-brane n
ear an orientifold O7-plane, whose stable non-BPS state was identified befo
re, (ii) the exotic affine E-1 algebra, whose stable non-BPS state seems to
be genuinely non-perturbative, and, (iii) the affine E-2 algebra represent
ing a D7-brane near a pair of O7-planes. As a byproduct of our work we cons
truct explicitly all 7-brane configurations that can be isolated in a K3. T
hese include non-collapsible configurations of affine type.